Cytomegalovirus diagnostic reagent kits
Tests per kit: 96
Shelf life: 12 months
Storage at: 2-8°C
Time to result: <3 hours
ELISA reagent kit is destined for:
- detection of virus specific antibodies during sero-epidemiological research;
- detection of seronegative individuals in risk groups (for example, pregnant);
- definition of donor immune status regarding CMV;
- collection of plasma with high content of antibodies to CMV for immunoglobuline manufacturing;
- diagnostics of primary CMV infection (if paired sera available).
Parallel analyzing of serum with viral and control antigen allows to exclude false positive results.
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Tests per kit: 48
Shelf life: 12 months
Storage at: 2-8°C
Time to result: 2 hours
Reagent kit "BioPrime-CMV" is destined for definition of avidity index of specific G class immunoglobulin to CMV and for diagnostics of primary CMV infection. The method is based on detection of "early" low avidity IgG, which appear in case of primary infection and stay in blood during 1-2 months. The method is alternative to detection of virus-specific M class antibodies and does not require paired sera.
To define the avidity index if IgG antibodies each sample is tested in two parallel plate wells with immobilized herpes virus antigens. Specific to HSV human proteins antibodies interact with adsorbed antigens and produce immune complexes. After incubation with the tested serum experimental wells are additionally processed with denaturating solution, which destroys low avidity antibodies + antigen complexes, but does not influence high avidity complexes. Reduction of optical absorption in the well, processed with denaturating solution, in comparison with the control well, indicates presence of low avidity antibodies in the tested sample.
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Tests per kit: 48
Shelf life: 12 months
Storage at: 2-8°C
Time to result: 1 hour 15 minutes
ELISA reagent kit is destined for detection of antibodies to CMV main early protein in infection active phase.